Escalating Threat of HPAI H5N1 Clade 2.3.4.4b to Australia: Emerging Concerns from Sub-Antarctic Observations and Implications for National Preparedness and Biosecurity

Authors

  • Pan Zhang Biosecurity Program, Kirby Institute, Faculty of Medicine, University of New South Wales (UNSW), Sydney, NSW 2033, Australia
  • Raina MacIntyre Biosecurity Program, Kirby Institute, Faculty of Medicine, University of New South Wales (UNSW), Sydney, NSW 2033, Australia
  • Mohana Kunasekaran Biosecurity Program, Kirby Institute, Faculty of Medicine, University of New South Wales (UNSW), Sydney, NSW 2033, Australia
  • Abrar Chughtai School of Population Health, Faculty of Medicine, University of New South Wales (UNSW), Sydney, NSW 2033, Australia
  • Noor Bari Biosecurity Program, Kirby Institute, Faculty of Medicine, University of New South Wales (UNSW), Sydney, NSW 2033, Australia

DOI:

https://doi.org/10.31646/gbio.343

Keywords:

Heard Island, HPAI H5N1,, Clade 2.3.4.4b, Australia

Abstract

The Australia mainland has thus far remained free from incursions of highly pathogenic avian influenza (HPAI) H5N1 clade 2.3.4.4b; however, the threat is escalating, particularly considering detections of the virus in Antarctica and Sub-Antarctic regions. While the East Asian-Australasian Flyway (EAAF) has been the primary hypothesised route for potential introduction, the emergence of cases in southern polar regions also highlights the need to consider the Southern Ocean Flyway as a credible transmission pathway.

Published

2026-03-11

How to Cite

Zhang, P., MacIntyre, R., Kunasekaran, M., Chughtai, A., & Bari, N. (2026). Escalating Threat of HPAI H5N1 Clade 2.3.4.4b to Australia: Emerging Concerns from Sub-Antarctic Observations and Implications for National Preparedness and Biosecurity. Global Biosecurity, 8(88). https://doi.org/10.31646/gbio.343

Issue

Section

Research Articles
Received 2025-11-07
Accepted 2026-01-28
Published 2026-03-11